Rabu, 24 April 2013

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Handbook of Pharmacogenomics and Stratified MedicineFrom Academic Press

Handbook of Pharmacogenomics and Stratified Medicine is a comprehensive resource to understand this rapidly advancing field aiming to deliver the right drug at the right dose to the right patient at the right time. It is designed to provide a detailed, but accessible review of the entire field from basic principles to applications in various diseases. The chapters are written by international experts to allow readers from a wide variety of backgrounds, clinical and non-clinical (basic geneticists, pharmacologists, clinicians, trialists, industry personnel, ethicists) to understand the principles underpinning the progress in this area, the successes, failures and the challenges ahead. To�be accessible�to the widest range of readers, the clinical application section introduces the disease process, existing therapies, followed by �pharmacogenomics and stratified medicine details.

Medicine is�the cornerstone of modern therapeutics prescribed on the basis that its benefit should outweigh its risk. It is well known that people respond differently to medications and in many cases the risk-benefit ratio for a particular drug may be a gray area. The last decade has seen a revolution in genomics both in terms of technological innovation and discovering genetic markers associated with disease. In parallel there has been steady progress in trying to make medicines safer and tailored to the individual. This has occurred across the whole spectrum of medicine, some more than others. In addition there is burgeoning interest from the pharmaceutical industry to leverage pharmacogenomics for more effective and efficient clinical drug development.

  • Provides clinical and non-clinical researchers with practical information normally beyond their usual areas of research or expertise
  • Includes an basic principles section explaining concepts of basic genetics, genetic epidemiology, bioinformatics,� pharmacokinetics and pharmacodynamics
  • Covers newer technologies– next generation sequencing, proteomics, metabolomics
  • Provides information on animal models, lymphoblastoid cell lines, stem cells
  • Provides detailed chapters on a wide range of disease conditions, implementation and regulatory issues
  • Includes chapters on the global implications of pharmacogenomics

  • Sales Rank: #3263811 in Books
  • Published on: 2014-05-20
  • Original language: English
  • Number of items: 1
  • Dimensions: 11.00" h x 2.20" w x 8.60" l, 7.40 pounds
  • Binding: Hardcover
  • 1118 pages

Review

"…a comprehensive resource to understand this rapidly advancing field aiming to deliver the right drug at the right dose to the right patient at the right time."--Anticancer Research, January 2015

"This is an extremely useful resource for clinicians, scientists, or any individuals interested in an excellent review of the rapidly advancing field of pharmacogenomics and its increasing relevance for clinical practice. - Rating: 5 Stars"--Doody's.com, 03-Oct-14

About the Author
Dr Sandosh Padmanabhan is a Reader and Honorary Consultant Physician at the Institute of Cardiovascular and Medical Sciences, University of Glasgow. His research spans the genetics of cardiovascular traits, pharmacogenomics and stratified medicines and hypertension epidemiology.

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Sabtu, 20 April 2013

[I700.Ebook] Ebook Free Phenomenological Interpretation of Kant's Critique of Pure Reason (Studies in Continental Thought), by Martin Heidegger

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Phenomenological Interpretation of Kant's Critique of Pure Reason (Studies in Continental Thought), by Martin Heidegger

The text of Martin Heidegger’s 1927–28 university lecture course on Emmanuel Kant’s Critique of Pure Reason presents a close interpretive reading of the first two parts of this masterpiece of modern philosophy. In this course, Heidegger continues the task he enunciated in Being and Time as the problem of dismatling the history of ontology, using temporality as a clue. Within this context the relation between philosophy, ontology, and fundamental ontology is shown to be rooted in the genesis of the modern mathematical sciences. Heidegger demonstrates that objectification of beings as beings is inseparable from knowledge a priori, the central problem of Kant’s Critique. He concludes that objectification rests on the productive power of imagination, a process that involves temporality, which is the basic constitution of humans as beings.

  • Sales Rank: #1446133 in Books
  • Published on: 1997-11-22
  • Released on: 1997-11-22
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.25" h x 1.28" w x 6.12" l, 1.42 pounds
  • Binding: Hardcover
  • 320 pages

Language Notes
Text: English (translation)
Original Language: German

From the Back Cover
The text of Martin Heidegger's 1927-28 university lecture course on Emmanuel Kant's Critique of Pure Reason presents a close interpretive reading of the first two parts of this masterpiece of modern philosophy. In this course Heidegger continues the task he enunciated in Being and Time as the problem of dismantling the history of ontology, using temporality as a clue. Within this context the relation between philosophy, ontology, and fundamental ontology is shown to be rooted in the genesis of the modern mathematical sciences. Heidegger demonstrates that objectification of beings as beings is inseparable from knowledge a priori, the central problem of Kant's Critique. He concludes that objectification rests on the productive power of imagination, a process that involves temporality as the basic constitution of humans as beings. This is an essential work for students of Heidegger, Kant, modern philosophy, and contemporary phenomenology.

About the Author

Parvis Emad is Emeritus Professor of Philosophy at DePaul University and the founding co-editor (with Kenneth Maly) of Heidegger Studies. Also with Maly, he has translated Hegel’s Phenomenology of Spirit by Martin Heidegger and Encounters and Dialogues with Martin Heidegger by Heinrich Wiegand Petzet.

Kenneth Maly is Professor of Philosophy at the University of Wisconsin-LaCrosse and co-editor (with John Sallis) of Heraclitean Fragments. With Parvis Emad he is currently translating Beitr�ge zur Philosophie (Vom Ereignis) by Martin Heidegger.

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20 of 46 people found the following review helpful.
Kantbuch before the fact
By steven schwartzbard
A lecture course that eventually became the famous Kantbuch, Heidegger demonstrates his remarkable capacity to think in complete sentences. The reading of Kant is decidedly Aristotlizing, with the priority of the imagination (phantasia) over reason (nous) or sense (aisthesis), and the priority of imagination cannot be separated from the priority of time, the gift which is self giving (or in Kant, self-affection: masturbation). The most clever thing that H does, and which he refrains from in the Kantbuch, is to turn the categories (quantity, quality, modality, and something else) into emanations of past, present, future. H reads modern philosophy as the triumph of the imagination, and that is no clearer than in Kant, but for Heidegger, the future possesses a priority, and the future is "image-poor." The connection of imagination with manipulation (and potentiality) leads some (like Sartre) to identify imagination with negativity, but H wants no part of this "humanism." Imagination and time may possess a priority that Kant "recoils" from, but H demonstrates the reductio in Kant's argument not to valorize imagination but ironically to resuscitate aisthesis, or the potentia passiva, the ability or power to receive, to listen intently, or just to listen.

0 of 2 people found the following review helpful.
Five Stars
By Jos� Monserrat Neto
I WANT TO SEE THE TABLE CONTENTS OF AMAZON BOOKS!!!

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Excellent but a quick comment
By Ahmad Mohmand
The Product is excellent. However, the cover is missing. Could someone please answer me why the product's cover is missing. I really wanted the cover too.

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Selasa, 16 April 2013

[Q189.Ebook] Get Free Ebook Legal Writing in Plain English, Second Edition: A Text with Exercises (Chicago Guides to Writing, Editing, and Publishing), by Bryan A. Ga

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Legal Writing in Plain English, Second Edition: A Text with Exercises (Chicago Guides to Writing, Editing, and Publishing), by Bryan A. Ga

Admirably clear, concise, down-to-earth, and powerful—all too often, legal writing embodies none of these qualities. Its reputation for obscurity and needless legalese is widespread. Since 2001 Bryan A. Garner’s Legal Writing in Plain English has helped address this problem by providing lawyers, judges, paralegals, law students, and legal scholars with sound advice and practical tools for improving their written work. Now the leading guide to clear writing in the field, this indispensable volume encourages legal writers to challenge conventions and offers valuable insights into the writing process that will appeal to other professionals: how to organize ideas, create and refine prose, and improve editing skills.
Accessible and witty, Legal Writing in Plain English draws on real-life writing samples that Garner has gathered through decades of teaching experience. Trenchant advice covers all types of legal materials, from analytical and persuasive writing to legal drafting, and the book’s principles are reinforced by sets of basic, intermediate, and advanced exercises in each section.
�In this new edition, Garner preserves the successful structure of the original while adjusting the content to make it even more classroom-friendly. He includes case examples from the past decade and addresses the widespread use of legal documents in electronic formats. His book remains the standard guide for producing the jargon-free language that clients demand and courts reward.

  • Sales Rank: #20165 in Books
  • Published on: 2013-08-26
  • Released on: 2013-08-26
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.25" h x .80" w x 6.50" l, .96 pounds
  • Binding: Paperback
  • 256 pages

Review
“Interspersed with rules of good writing is a revolutionary manifesto packaged in a plain gray wrapper. This book won’t draw attention merely by sitting on your shelf, but if you put certain pieces of its advice in the next legal document you draft, you are sure to raise the eyebrows of any lawyer who reads it.” (Trial)

“This magnificent book explains every major principle of plain legal writing in a way that no other book has ever done. Based on years of Garner’s research and teaching, this book elevates the standard of what a legal-writing text can and should be. Get a copy for every law student, lawyer, and legislator that you know.” (Mark E. Wojcik, John Marshall Law School)

"This easy-to-follow guide is useful both as a general course of instruction and as a targeted aid in solving particular legal writing problems." (Harvard Law Review)

"Garner's work is a significant improvement [over other books] . . . . Those who are willing to approach the book systematically and to complete the exercises will see dramatic improvements in their writing." (Law Library Journal)

“The importance of improving writing skills . . . is� also the central theme of one of my favourite books of the year: Garner’s Legal Writing in Plain English. Much more exciting than the title suggests, it leads the reader through a series of observations and exercises to develop a simple, clear and elegant writing style. My only regret is that it is written for a US market with corresponding examples. There is surely a need for a UK version, which should routinely be given to all law students, trainees and even some senior partners.” (Sarah Greer Times Higher Education Textbook Guide (UK))

About the Author
Bryan A. Garner is president of LawProse, Inc., and the Distinguished Research Professor of Law at Southern Methodist University. The editor-in-chief of Black’s Law Dictionary, Garner is the author of several best-selling books, including Garner’sModern American Usage and, with Justice Antonin Scalia, Reading Law: The Interpretation of Legal Texts and Making Your Case: The Art of Persuading Judges.

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15 of 16 people found the following review helpful.
Excellent
By L Parker
If you've read Garner's stuff, you'll notice some overlap. This book restated "The Winning Brief" multiple times, and it has most of the same examples (Demand Letters, Memos, etc.) as "The Redbook 2d" (I don't have the 3d of that one).

That's the disclaimer. But I still loved the book. It's largely written as a how-to, gives you tips to improve your legal writing, and is a resource that I'll continue to reference throughout my career.

If you'd like a quick read (with accompanying exercises to test your skill) this is a great book to have. Then, when you become more interested, you can nab the Redbook, Legal Usage dictionaries, etc. In sum, it's a great place to start.

One objection, though: Garner's answers in the back often deal with only the Easy exercise, not all three (Easy, Intermediate, Hard). I realize that giving answers to all three would lengthen the book, but the easy one is exactly that--easy. I'd like to see his Heller brief, or any of the harder ones just to compare. But that's only a minor annoyance. Otherwise, it's a real asset if you're interested in improving your legal writing. And you should be.

6 of 6 people found the following review helpful.
Who knew?
By Ross
This book was purchased for a tax research class. It absolutely delivers on its title, more than I even could have imagined. I was immediately impressed by the author's matter-of-fact yet engaging style, and the content is quite useful for non-legal professionals too. If you ever write persuasive letters, articles or blog posts, there are many practical tips in this book. It is an entertaining and thought provoking read. After most sections, I was left scratching my head with a puzzled look on my face. Not questioning the author's ideas, I was instead left wondering why they were not more mainstream, legal and otherwise. I really hope many more people, even those who only occasionally write, read this book!

4 of 4 people found the following review helpful.
Let's be clear about what this is
By Denise Greene
If you're looking for a text to substitute for a Pre-Law English course, this might be its best application. If you're a professor or English instructor looking for a great text to teach Pre-Law English, it's worth a look. It could also be good for someone already in the law field who has been writing "Legalese" and needs to learn a better way. This book can teach how to distill the core of a matter and how to change unclear thought into something coherent and succinct.

Amazon's rating system is, unfortunately, about how well I liked it, not how useful it might be to others. To be fair (which is why I gave it a 3 instead of a 2), I have an MA in English Rhetoric and have spent my life in the writing/publishing world, so it does not fit my needs. I'm new to the field of law and hoped it would teach me the required elements of various briefs/documents. Out of a 240 page book, about 50 pages is devoted to what I sought (Appendix B - Four Model Documents on drafting an Appellate Brief, Motion, Contract, and a Research Memo). Appendix A is "How to Punctuate" which, ostensibly, if you're over 30, you learned in school somewhere along the line.

The remainder of a book is simply an advanced writing course with examples drawn from legal documents. A typical example would be that you are given a convoluted sentence which you then have to break into smaller, more succinct and understandable sentences. The advanced form of that same exercise is a convoluted paragraph in which you have to figure out what is being said and rewrite it to make it more clear and coherent. Other exercises involve interviewing lawyers and judges to find out their preferences in what they like to read as far as legal documents are concerned. The book also assumes you have access to a law library and lots of time to research. One example is: "Find a judicial opinion that takes several paragraphs before getting to the point."

Be more diligent than I was -- take a look at the Table of Contents from the "Look Inside" link, and even download a sample of it to your Kindle before purchasing. Apparently I simply looked at the reviews.

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Senin, 08 April 2013

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Because of Thursday, by Patricia Polacco

From critically acclaimed author Patricia Polacco comes a heartwarming story about a girl named Annie, her lucky Thursdays, and a special cat who comes into her life just in time to make everything right.

Thursdays have always been lucky for Annie Fetlock. She was born on a Thursday. She won her first cooking contest at the age of eight on a Thursday. She met the love of her life, Mario, on a Thursday. They were married on a bright Thursday afternoon and their two children were both born on a Thursday. Annie is known far and wide for her Poke Pasta Salad and has the most popular restaurant for miles around.

When Mario suddenly passes away, Annie’s joy and love of cooking disappears. Before too long, a little kitty appears and Annie takes the kitty in, and, of course, calls it Thursday. Annie is back making Poke Salad in no time. Thursday the cat is known for amazing twirls and tricks and one day his twirls land him in Annie’s draining rigatoni, causing the pot of hot oil, garlic, and peppers to spill into the pasta! Then the entire container of Parmesan cheese overturned into the mix. The customers were horrified until they noticed that what looked like a big mess had the most amazing aroma and turned out to be the most delicious pasta dish ever created! Ugly Pasta—the dish that would make Annie famous for miles around—was born. And of course it was a Thursday!

  • Sales Rank: #36661 in Books
  • Published on: 2016-10-18
  • Released on: 2016-10-18
  • Original language: English
  • Number of items: 1
  • Dimensions: .0" h x .0" w x .0" l, .0 pounds
  • Binding: Hardcover
  • 40 pages

Review
A grieving widow finds a new lease on life and unexpected material success after adopting a stray cat.Annie and her husband, Mario, happily run a small diner in a small town. As the white couple grows older, the two continue to enjoy their low-key life—until Mario falls ill and dies. Annie's subsequent sadness mutes her enthusiasm for cooking. The discovery of a kitten on her porch—the titular Thursday—revitalizes her and, eventually, results in the creation of an entirely new recipe. Annie doesn't just reopen the original diner, she brands her new dish Ugly Pasta, adds national franchises, builds a factory to employ her neighbors, and spends her profits on civic improvements. Polacco's signature scratchy illustrations, rendered in pencil and marker, are full of energy. (Kirkus Reviews 7/15/16)

About the Author
Patricia Polacco belongs to a family of storytellers, poets, farmers, teachers, and artists. They came from many parts of the world, but mainly Russia. She grew up to be an illustrator, a designer, and creator of many beloved children’s books, including The Keeping Quilt, The Blessing Cup, Fiona’s Lace, The Trees of the Dancing Goats, Babushka’s Doll, and My Rotten Redheaded Older Brother. She lives in Union City, Michigan. Visit her at PatriciaPolacco.com and follow her on Facebook.

Patricia Polacco belongs to a family of storytellers, poets, farmers, teachers, and artists. They came from many parts of the world, but mainly Russia. She grew up to be an illustrator, a designer, and creator of many beloved children’s books, including The Keeping Quilt, The Blessing Cup, Fiona’s Lace, The Trees of the Dancing Goats, Babushka’s Doll, and My Rotten Redheaded Older Brother. She lives in Union City, Michigan. Visit her at PatriciaPolacco.com and follow her on Facebook.

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Sabtu, 06 April 2013

[Z839.Ebook] Get Free Ebook The Photographer : Female Domination, Forced Feminization, BDSM & Male Chastity, by Maia Anne Fisher

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The Photographer : Female Domination, Forced Feminization, BDSM & Male Chastity, by Maia Anne Fisher

Female Domination, Forced Feminization, Male Chastity, Humiliation, Bondage, Discipline, Pegging, Strap-on play, all with dubious consent.
This story revisits the lovely 'Sadistic Sadie' from 'Human Dog : Puppy Play Erotica'. David is in town to sign on, he calls for a pint while he's there and gets mocked for being a 'dole dosser' by a beautiful female photographer who joins him at the bar. He claims he wants to work and that he'd take anything that was offered to him, what he didn't realize was that he was about to be offered a job a model for fetish, BDSM, female domination and Forced Feminization photographs. After being more or less bullied into agreeing to it he finds himself driven to her studio only to be directed into performing humiliating acts for her camera, cross-dressing and acting quite the sissy. At the end of the shoot, he's ended up locked into a severe and cruel 'Kali's Teeth Bracelet' or KTB chastity device, which prevents erections and playing with himself. His dominant photographer has taken a shine to him though and though she doesn't have the key to his device, offers for him to stay for a while afterwards. His treatment as a submissive and her constant verbal humiliation of him has a profound effect on him, making him more and more submissive. When he gets home that night, still locked firmly in the KTB chastity device and partially feminized, he finds his sister taking advantage of his situation and humiliating him further.

The next day, he begins by being further feminized at the Beautician's and then finds the mysterious, dominant girl he saw leading a guy out of the 'Highway Man' the previous week is going to be the female model dominating him. Just when things couldn't get any worse he finds himself on the receiving end of severe corporal punishment, in the shape of spanking and caning for the camera, then he gets the full forced feminization treatment as he's turned into a submissive, chaste, sissy maid. The final insult comes when Sadie violates him for the camera, giving him a pegging whilst feminized and in chastity that he will never forget.

At the end of the shoot, Helen has enjoyed using him as both her model and sissy slave she offers him a choice, take the royalty payments and go, or become her live-in, chaste sissy maid and fetish photography model.

Warning this work contains elements of:-
Femdom
Female Domination
Forced Feminization
Male Chastity (Kali's Teeth Bracelet Chastity Device)
Bondage & Restraints
Forced Feminization
Sissification
Cross-Dressing
Corporal Punishment (Caning and Over-the-knee Spanking)
Pegging
Slavery
Sissy Maid
Orgasm Denial
Forced Oral
Black Mail

This is NOT intended to be realistic, please only buy if you are not likely to be offended and if it is legal to purchase in your country of residence. I do not condone any of the acts portrayed in this story.

Also by the same author:-

Human Dog : Puppy Play Erotica
Femdom & Extreme BDSM : A Night to Remember, A Life Dismantled

  • Sales Rank: #555364 in eBooks
  • Published on: 2013-10-25
  • Released on: 2013-10-25
  • Format: Kindle eBook

Most helpful customer reviews

2 of 2 people found the following review helpful.
Maia makes us truly believe in David’s descent into sissy submission
By Sally Bend
You can really tell when an author is enjoying herself, and when she truly shares the fantasy that she’s put upon the page. There’s a passion to those kinds of stories, and an attention to detail that shines through every erotic, humiliating moment. ‘The Photographer’ is one of those books, with a set-up that Maia Anne Fisher describes as “such a delicious scenario” she just had to write it.

Female domination, forced feminization, bondage, chastity, corporal punishment, pegging, and sissy maid slavery – it’s all here, and it’s all intricately tied together in a delicious package. While some authors cheat or cut corners by ‘revealing’ a character had feminine desires all along, Fisher goes for a complete breaking and conditioning, making us truly believe in David’s descent into sissy submission. Through her words, we experience David’s transformation from embarrassment and shame, to pride and pleasure. What’s more, she rewards the reader with a happily-ever-after ending that will leave you longing for the caress of a collar, the bite of a chastity device, and the fullness of sissy penetration.

2 of 2 people found the following review helpful.
Things Are Not Always What They Seem
By bleacher creacher
A bloke down on his luck , almost pennyless , meets a woman photoghapher in a bar . She offers him a job , as her model , but he must agree to wearing feminine lingerie , for a shoot she's been hired to do . If her work is accxepted , there will be a paycheck for him . She says he has the right feminine look for what she needs , is she right ? Can he do this for her ? You'll have to read the book to find out .

2 of 2 people found the following review helpful.
A fun kinky read
By Amazon Customer
Fun, well-written, entertaining story with a briskly paced progression into the promised kinks. The book description pretty much lays out what you should expect, with the focus being on the first half of the kinks mentioned (Female Domination, Forced Feminization
Male Chastity (Kali's Teeth Bracelet Chastity Device), Bondage & Restraints, Sissification)

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[E998.Ebook] PDF Ebook Television, the Public Sphere, and National Identity, by Monroe E. Price

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Television, the Public Sphere, and National Identity, by Monroe E. Price

What is meant by an "independent" television and press, and what affirmative role should any government have in the regulation of television? How do competing interest groups use media regulation to their advantage? What impact does television have on democratic values and the process of democracy itself? Television, the Public Sphere, and National Identity focuses on these and other questions in a broad reinterpretation of television's role and influence on democratic societies in a time of increased globalization of the media.

  • Sales Rank: #4035911 in Books
  • Published on: 1996-02-29
  • Original language: English
  • Number of items: 1
  • Dimensions: 8.50" h x .73" w x 5.44" l, .80 pounds
  • Binding: Paperback
  • 312 pages

Review
`Monroe Price has written an interesting and often thought-provoking book ... In a single work he has brought together a great range of concerns and insights regarding the proper relationship of democratic states and the electronic media in an era of globalization.'
Perry Keller

About the Author
Monroe E. Price is the Danciger Professor of Law at the Benjamin N. Cardozo School of Law, Yeshiva University.

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Rabu, 03 April 2013

[Y123.Ebook] Fee Download Gemba Walks, Expanded 2nd Edition, by Jim Womack

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Gemba Walks, Expanded 2nd Edition, by Jim Womack

In 12 new essays ranging from the provocative to the practical, and written specially for the second edition of Gemba Walks, author and management expert Jim Womack reflects on the past 30 years of lean and assesses the current state of lean today.

He also shares thoughts on how lean thinking and practice can continue to make the world a better place by gaining traction in areas such as government and health care, provides practical guidance for how leaders everywhere can realize the full benefits of a lean management system, and shares hope for continued improvement on the path to better work and more value.

Over the past 30 years, Womack has developed a method of going to visit the gemba at countless companies and keenly observing how people work together to create value. He has shared his thoughts and discoveries from these visits with the lean community through a monthly letter. With Gemba Walks, Expanded 2nd Edition, Womack has selected and reorganized his key letters and written 12 new essays.

Gemba Walks shares his insights on topics ranging from the application of specific tools to the role of management in sustaining lean as well as the long-term prospects for this fundamental new way of creating value. Hearing this book will reveal to listeners a range of lean principles as well as the basis for the critical lean practice of go see, ask why, and show respect.

  • Sales Rank: #13869 in Audible
  • Published on: 2015-07-28
  • Format: Unabridged
  • Original language: English
  • Running time: 597 minutes

Most helpful customer reviews

4 of 4 people found the following review helpful.
Gemba Walks 2 - Essential to Horizontal Value Stream Flow Success
By David C. Hogg
Seeing exactly what's before us is critical to building the 'Right Vision.' Womack's new book adds to his earlier & still valuable "Gemba Walks", 12 new - highly relevant - essays. They include the facts about the emergence of 'Lean' - as told by the man who was there making it happen. There is no further need to rely on the multitude of hearsay versions. Of high interest is the essay shedding clarity into why 2014 is the 100th anniversary of true 'Lean' which began in Highland Park MI. He provides the facts from which he bestows on that first site as the true "Temple of Lean' - much of which can be found today in the world-leading Toyota Production System. For many, this will be eye-opening as he puts into perspective the last 25 years of lean. But this edition stays true to the earlier edition driving home to leaders the shear power of 'Gemba Walks' to enable them to see what is really there. One wonders - how could a right 'True North Vision' be determined without such Walks. He sobers us to see the huge reservoirs of waste yet untouched. What's truly unique - the book is written by the greatest plant Walker alive today - and he is openly sharing what he looks for, and what he sees. He executed one of the largest business investigations ever - and refused to trust data from a host site that resisted his walk. If you see the evolution to a single Horizontal Value Stream Flow plant in your future - this is the book that will provide the eyes to see what's to be done to out-compete your competitors.

0 of 0 people found the following review helpful.
Good book to understand the basics and Excellent opportunity to learn from experts experience
By Dillibabu
The experience shared in this book is invaluable and i have gained lot of knowledge. The examples about Lean implementation in TVS Group (Brakes India) and Wabco-TVS is an eye opener. It shows clearly that Leadership vision and employee engagement is paramount for successful Lean implementation in any geography. Do not try to get into the trap of implementation...study yourself and adapt it to your condition...Thats how TVS group is successful...
A Must read for all Leadership....Deming's philosophy of "System Thinking of profound knowledge" holds true still...Leader who have not practiced and experimented himself (Servant Leadership) cannot able to implement or sustain Lean...
Eye opener...chapters namely
The Worst form of Muda
Mura?Muri?Muda?
Constancy of purpose
The power of precision process etc.,

0 of 0 people found the following review helpful.
great reference for any gemba
By srivatsa
Yes, this is a great reference for managers whose responsibility is to help identify and solve problems,
it provides enough thought provoking ideas that help in asking the right questions. and learning to look for value & waste
the learnings can be used at any industry or sector and is not for manafacturing alone.
I have used the knowledge to help coach other members when i go to the Gemba, thanks a lot

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